Glenohumeral Arthritis


Glenohumeral (shoulder) arthritis is a common source of pain and disability that affects up to 20% of the older population. Damage to the cartilage surfaces of the glenohumeral joint (the shoulder's "ball-and-socket" structure) is the primary cause of shoulder arthritis.

There are many treatment options for shoulder arthritis, ranging from pain medications and exercises for mild cases, to surgical procedures for severe cases. Treatment decisions are based upon the cause, the symptoms and the severity of the patient's disease. Each year, over 10,000 shoulder replacement surgeries are performed in the United States to relieve pain and improve function for shoulders that are severely damaged by glenohumeral arthritis.

What does the inside of the shoulder look like?

The shoulder is the most mobile joint in the human body with a complex arrangement of structures working together to provide the movement necessary for daily life. Unfortunately, this great mobility comes at the expense of stability. Several bones and a network of soft tissue (ligaments, tendons, and muscles), work together to produce shoulder movement. They interact to keep the joint in place while it moves through extreme ranges of motion. Each of these structures makes an important contribution to shoulder movement and stability. Certain work or sports activities can put great demands upon the shoulder, and injury can occur when the limits of movement are exceeded and/or the individual structures are overloaded. Click here to read more about shoulder structure.

What is the labrum and what does it do?

The labrum is a disk of cartilage on the glenoid, or "socket" side of the shoulder joint. The labrum helps stabilize the joint and acts as a "bumper" to limit excessive motion of the humerus, the "ball" side of the shoulder joint. More importantly, it holds the humerus securely to the glenoid, almost as if suction were involved. Although the glenoid itself is a relatively flat surface, the labrum's cuff-like contour gives the glenoid a more concave shape. The secure but flexible fit of the humerus within the glenoid permits the great range motion of the healthy shoulder.

What is glenohumeral joint arthritis?

Glenohumeral joint arthritis is caused by the destruction of the cartilage layer covering the bones in the glenohumeral joint. This creates a bone-on-bone environment, which encourages the body to produce osteophytes (bone spurs). Friction between the humerus and the glenoid increases, so the shoulder no longer moves smoothly or comfortably. As osteophytes develop, motion is gradually lost. A number of conditions can lead to the breakdown of cartilage surfaces:

  • Wear and tear over time
  • Trauma (such as a fracture or dislocation)
  • Infection
  • A chronic (long-standing) inflammatory condition (such as rheumatoid arthritis)
  • Osteonecrosis (bone death caused by loss of blood supply)
  • Chronic rotator cuff tears in which the head of the humerus (the upper bone in the arm) loses its proper position in the middle of the glenoid (socket)
  • Rare congenital and metabolic conditions
  • Post-surgical changes that can be a result of over-tightening during instability surgery
Shoulder Structure

Bones and Joints

The bones of the shoulder:

  • The humerus is the upper arm bone. This is the "ball" of the shoulder's "ball and socket" joint.
  • The scapula is the flat, triangular bone commonly called the shoulder blade. Prominent areas of the scapula serve as attachment points for many muscles and ligaments.
    • The glenoid is the shallow "socket" on the side of the scapula that receives the 'ball' of the humerus. Together they form the "ball and socket" arrangement of the shoulder.
    • The scapular spine is a horizontal ridge along the back of the scapula that divides the scapula into upper and lower regions.
    • The acromion is the end of the scapular spine. It projects up to form the top of the shoulder.
    • The coracoid process is a projection towards the front of the scapula and is an attachment site for several muscles and ligaments.
  • The clavicle is the collarbone. Although it appears to be straight, it actually forms an S-shape when seen from above.
  • The thorax or rib cage, is an anchor for several muscles and ligaments. Although the ribs do not physically attach to the scapula, the thorax stabilizes and maintains proper positioning of the scapula so that the arm can function to its fullest capacity.

Additionally, there are four bone junctions, or joints:

  • The glenohumeral joint is the main joint of the shoulder. Here, the glenoid on the scapula and the head of the humerus come together. The fairly flat socket of the glenoid surrounds only 20% - 30% of the humeral head. Because of its poor fit, this joint relies heavily on the surrounding soft tissue for support. The labrum, a ring of fibrocartilage tissue, attaches to the glenoid and deepens the socket to encircle more of the humerus.
  • The acromioclavicular joint, or AC joint, is the bony point on the top of the shoulder. It stabilizes the scapula to the chest, by connecting the acromion on the scapula to the clavicle, or "collarbone". A thick disk of fibrocartilage acts as a shock absorber between the two bones. The surrounding capsule and ligaments give this joint great stability.
  • The sternoclavicular joint, or SC joint, connects the other end of the clavicle to the sternum, or "breastbone". Like the AC joint, this joint contains a fibrocartilage disk that helps the bones achieve a better fit. It also gets excellent support from its joint capsule and surrounding ligaments.
  • The scapulothoracic articulation is the area where the scapula, embedded in muscle, glides over the thoracic rib cage. The surrounding muscles and ligaments keep the scapula properly positioned so that the arm can move correctly.


There are two types of cartilage in the shoulder:

  • Articular cartilage is the shiny white coating that covers the end of the humeral head and lines the inside surface of the glenoid. It has two purposes:
    • To provide a smooth, slick surface for easy movement
    • To be a shock absorber and protect the underlying bone
  • Fibrocartilage is the thick tissue that forms the disks of the AC and SC joints and the labrum, the ring that deepens the glenoid. Fibrocartilage has three roles:
    • To act as a cushion in shock absorption
    • To help stabilize the joint by improving the fit of the bones
    • To act as a spacer and improve contact between the articular cartilage surfaces


The shoulder relies heavily on ligaments for support. Ligaments attach bone to bone and provide the "static" stability in a joint. Ligaments will alternately become tight and loose with normal motion. They keep the joint within the normal limits of movement.

  • The glenohumeral ligaments attach in layers from the glenoid labrum to form the joint capsule around the head of the humerus.
  • The coracoacromial arch is the group of ligaments that spans the bony projections of the coracoid process and the acromion.
  • The coracoclavicular ligaments and the acromioclavicular ligament provide most of the support for the AC joint.

Muscles and Tendons

Muscles and tendons work together in the shoulder to provide the "dynamic" stability of the shoulder.

There are four muscle groups in the shoulder:

  • The rotator cuff muscles are the subscapularis, the supraspinatus, the infraspinatus, and the teres minor. They are the primary stabilizers that hold the "ball" of the humerus to the glenoid "socket". The socket is too shallow to offer much security for the humerus. These four muscles form a "cuff" around the humeral head, securing it firmly in the socket. As its name implies, this group of muscles also rotates the arm. The rotator cuff protects the glenohumeral joint from dislocation, allowing the large muscles that control the shoulder to power the arm with great mobility.
  • The biceps tendon complex also helps keep the humeral head in the glenoid and helps raise the arm.
  • The scapulothoracic muscles attach the scapula to the thorax. Their main function is to stabilize the scapula to allow for proper shoulder motion.
  • The superficial muscles of the shoulder are the large, powerful outer layer of muscles that are important to the overall function of the shoulder. This group includes the deltoid muscle, which covers the rotator cuff muscles.


A bursa is a pillow-like sac filled with a small amount of fluid. Bursae (plural) reduce friction and allow smooth gliding between two firm structures, like bone and tendon or bone and muscle. There are over 50 bursae in the human body; the largest is the subacromial bursa (under the acromion) in the shoulder. The subacromial bursa and the subdeltoid bursa (under the deltoid muscle) are often considered as one structure. This bursa separates the rotator cuff and the deltoid muscle, from the acromion.


What are the signs and symptoms of glenohumeral arthritis?

Pain from bone-on-bone rubbing within the joint is the most common symptom of glenohumeral arthritis

  • At first the pain may come and go, but it tends to increase with time, usually over several years.
  • Movement usually adds to the discomfort.
  • The pain is commonly present at night, and interferes with sleep.
  • There may or may not be pain at rest.

Loss of motion is another common symptom. Possible causes of motion loss include:

  • Osteophytes that block joint motion
  • Constriction of the joint capsule due to chronic inflammation, pain, and disuse
  • Fractures or previous surgeries that may have changed joint structure and interfered with motion
  • Weakness of the supporting muscles following a rotator cuff tear

Other symptoms may be:

  • Atrophy (wasting away) of shoulder muscles due to disuse
  • Swelling in the shoulder due to inflammation
  • Crepitus (clicking or crunching sound) during shoulder motion
  • Tenderness with palpation (touch) affecting the entire shoulder region or specific areas

How is glenohumeral arthritis diagnosed?

The doctor will first obtain a history of the patient's symptoms and health over the past several years. Those who suffer from shoulder arthritis typically report an increase in pain over several years. The doctor will ask if the patient has any conditions that may be the underlying cause of osteoarthritis such as:

  • Previous trauma or surgery to the shoulder
  • An infection in the shoulder
  • A previous rotator cuff tear
  • Osteoarthritis or rheumatoid arthritis in other joints

Next, the doctor will do a physical examination of the shoulder to evaluate the symptoms and reveal other conditions that may exist.

X-ray imaging of the shoulder can confirm a diagnosis of glenohumeral arthritis. With x-ray, the doctor can see structural changes that indicate arthritis, such as:

  • Irregularity of the joint surface
  • Osteophytes, typically located on the lower part of the joint
  • Bone erosion on the humeral head, glenoid, or both.
  • Glenoid bone loss is often visible on the backside of the joint.

Other imaging techniques used to make the diagnosis include:

  • CT-Scan (Computer Tomography) - This test shows the extent of glenoid bone loss and any anatomic abnormalities that may affect treatment.
  • Arthrogram - This technique is useful in the evaluation of rotator cuff tears
  • MRI (Magnetic Resonance Image) - Although not as commonly used to diagnose arthritis as other imaging studies, an MRI can provide detailed information about the soft tissue structures of the joint.

How is glenohumeral arthritis treated?

Non-Operative Treatment

Mild glenohumeral arthritis is often manageable with a regimen of:

  • Rest
  • NSAIDS (non-steroidal anti-inflammatory medicines) - such as ibuprofen or naproxen
  • Exercises to increase range of motion and strength

Mild to moderate glenohumeral arthritis pain is often effectively controlled by using any one or a combination of the following treatments:

  • Corticosteroid injections (cortisone shots) may be recommended for more severe cases that do not respond to NSAIDS. A concentrated dose of anti-inflammatory medicine is injected directly into the joint and can be safely used to manage most patients' pain. It does not cure the disease, however, and not all patients respond well to the injections. Eventually, corticosteroids lose their effectiveness for most patients' pain.
  • Glucosamine and chondroitin are non-prescription supplements that may help neutralize the destructive enzymes associated with osteoarthritis. They may also serve as building blocks for new cartilage formation. These compounds, which are available separately or in combination, have been shown to decrease arthritis pain in some clinical trials; however, more research is needed to evaluate the full extent of their effectiveness.
  • Viscosupplementation therapy improves the cushioning of the joint surfaces and has gained popularity in the last few years. Hyaluronic acid is injected directly into the joint in order to improve joint lubrication and reduce friction during movement. Hyaluronic compounds are generally safe although there have been reports of inflammatory reactions in patients treated with some preparations. Most of the studies on viscosupplementation have been done on the knee, so it is less clear what effects this type of treatment will have on the arthritic shoulder.

When severe shoulder arthritis pain is unmanageable with non-operative measures, surgical treatment may be recommended.

Operative Treatment

Debridement --Click here to read more about Debridement operative treatment

Shoulder Arthroplasty (Replacement) --Click here to read more about Shoulder Arthroplasty operative treatment

What types of complications may occur?

Even with the closest attention to detail, surgical complications may occur. Debridement surgery is typically less complex than arthroplasty. However, as with arthroplasty, the potential complications of bleeding, nerve injury, and infection are present.

Some of the more common complications are:

  • Infection - Perioperative antibiotics (given before and after surgery) and current intraoperative procedures have reduced infection rates in arthroplasty to less than 1%. If the infection is caught early, aggressive antibiotic treatment may save the components. A chronic infection that has been present for more that 6-12 weeks generally requires removal of the infected implant.
  • Blood loss - Although not usually considered a complication, blood loss is common during shoulder replacement surgery and a transfusion may be required. To avoid the concerns of disease transmission from a blood bank, the patient may choose to donate blood for use during the surgery, should it be necessary. Even though there are legitimate concerns about banked blood, the current blood available is extremely safe with very low incidences of disease transmission.
  • Nerve injury - Nerve injuries that occur during shoulder replacement surgery are usually temporary, with near normal function returning over time.
  • Component failure - This problem is more common with the glenoid component of a total shoulder arthroplasty. Usually, but not always, the loose glenoid component requires surgical removal.

Rehabilitation following shoulder arthroplasty or debridement requires teamwork between the patient, physician, and physical therapist. Good communication will optimize the patient's results and allow the earliest possible return to full activity.

  • During the first 6-8 weeks after surgery, the shoulder is usually immobilized with a sling.
  • During this time, the therapist will move the shoulder through passive range of motion exercises to prevent stiffness. This will allow the patient to maintain functional motion in the shoulder while protecting the soft tissue repair.
  • After the soft tissues are adequately healed (about 6-8 weeks) an active range of motion exercise program can begin.
  • Soon after adequate active range of motion is achieved, a strengthening program begins, concentrating on the rotator cuff muscles and those that stabilize the scapula.
  • Once appropriate levels of motion and strength are reached, a maintenance program of shoulder exercises, as part of a whole-body fitness regimen, is recommended. The patient who commits to a lifetime physical therapy program will maximize the success of the surgical procedure.
  • Return to full activity is highly variable among patients. Generally, complete recovery takes 4-6 months.

How painful is shoulder replacement surgery?

Shoulder arthroplasty is a complex procedure, which requires a great amount of cutting of deep tissues and bone. The surgeon takes great care to eliminate pain with appropriate analgesia both immediately after surgery and during the rehabilitation process. A long acting local anesthetic infused around the nerves of the joint is often used with general anesthesia during surgery. These regional blocks will provide several hours of pain relief even after a patient has emerged from general anesthesia. A patient-controlled intravenous infusion pump (PCA) is used in the early post-operative period for pain control. By the second or third day after surgery, oral pain relief medication is adequate through the early rehabilitation period (4-6 weeks).

How long before I can return to my normal activities after shoulder arthroplasty?

The time it takes to return to normal activity varies greatly from patient to patient. Most individuals have less pain at night or at rest in the first 2-4 weeks after surgery. Pain with activity persists longer, but generally decreases as the strength and function of the shoulder muscles improve. Full recovery usually takes 4-6 months.

What activities can I safely do after shoulder replacement?

The goal of shoulder arthroplasty is to relieve the pain from glenohumeral arthritis. It is unrealistic to expect to return to repetitive, heavy, overhead activities, which would put the replacement components at risk. Shoulder function after arthroplasty is also unlikely to allow the motions required by these activities.

According to the American Shoulder and Elbow Society, the acceptable activities after a shoulder arthroplasty are:

  • bowling, doubles tennis, cross-country skiing, swimming, canoeing, and shuffleboard
  • for those with previous experience in the activity: golf, ice skating, shooting, and downhill skiing

Unacceptable activities are:

  • football, gymnastics, hockey, rock climbing
  • throwing sports, except for gentle underhand tossing

I've heard that joint replacements sometimes "wear out" and need to be redone.

What are the chances I may require a second shoulder arthroplasty?

Long-term studies show that 85-90% of total shoulder replacements are functioning well ten years after implantation, and 75-85% are doing well fifteen years after surgery. Over time, current advances in materials and techniques should improve these percentages even more.


Gartsmann GM, Roddey TS, Hammerman SM. Shoulder arthroplasty with or without resurfacing of the glenoid in patients who have osteoarthritis. Journal of Bone and Joint Surgery. 82-A: pp 26-34, 2000.

Sperling JW, Cofield RH, Rowland CM. Neer hemiarthroplasty and Neer total shoulder arthroplasty in patients fifty years old or less: Long-term results Journal of Bone and Joint Surgery. 80-A: pp 464-73, 1998.

Lynch NM, Cofield RH, Silbert PL, Hermann RC. Neurologic complications after total shoulder arthroplasty. Journal of Shoulder and Elbow Surgery. Vol 5: pp53-61, 1996.

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